A Clinical Study of Addison's Disease

نویسندگان

  • G De Rosa
  • S M Corsello
  • L Cecchini
  • S Della Casa
  • A Testa
چکیده

Fifty-four patients affected by primary adrenocortical insufficiency have been retrospectively studied. Eighteen were affected by a tuberculous Addison's disease, 24 by an idiopathic Addison's disease and 12 by an unclassifiable form. Modality of arise, clinical presentation and association with other diseases are reviewed. The most useful laboratory and instrumental tests for the diagnosis are discussed and a diagnostic flow-chart is proposed.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Premature mortality in patients with Addison's disease: a population-based study.

BACKGROUND The survival rate of patients with primary adrenal insufficiency (Addison's disease) undergoing currently accepted replacement therapy is not known, although well-informed patients are considered to have a normal survival rate. In this study, we evaluated the mortality of patients with Addison's disease in Sweden. METHODS A population-based, retrospective, observational study was p...

متن کامل

The neuropsychiatric profile of Addison's disease: revisiting a forgotten phenomenon.

One hundred fifty years since Thomas Addison's original description of the disease, it is not commonly appreciated that patients with Addison's disease may present with psychiatric symptoms. A review of the literature indicates that disturbances in mood, motivation, and behavior are associated with Addison's disease. Psychosis occurs less frequently, but can be the presenting symptom of a life-...

متن کامل

Atypical Addison's disease in the dog: a retrospective survey of 14 cases.

Fourteen dogs diagnosed with Addison's disease and having atypical serum electrolyte levels are described. Seventy-eight percent were female, and most showed signs of inappetence, weakness, or vomiting. Ninety-three percent of the cases had either hyponatremia without hyperkalemia or normal serum electrolyte concentrations. Hemogram features were variable and were not useful in suggesting a dia...

متن کامل

Increase Serum Aminotransferases in Addison\'s Patients

SUMMARY Three pa ticnts admitted because of slightly increased serum amino trans fcrases were found to have Addison's disease. A review of 16 other patients with addison 's disease who had serum aminotransferase activity (aspartate aminotrans­ferase (ASAT) and alanine aminotransferase (ALAT) J determined prior to treatment revealed one more patient with slightly increased aminotransferase acti...

متن کامل

DRB1*04 and DQ alleles: expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease.

Of 957 patients with type 1 diabetes without known Addison's disease 1.6% (n = 15) were positive for 21-hydroxylase autoantibodies. Among DQ8/DQ2 heterozygous patients, the percentage expressing 21-hydroxylase autoantibodies was 5% (10 of 208) vs. less than 0.5% of patients with neither DQ8 nor DQ2. Three of the diabetic patients found to have 21-hydroxylase autoantibodies on screening were sub...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 67  شماره 

صفحات  -

تاریخ انتشار 1987